Endocrine Abstracts

Introduction: It is suggested that hyperuricemia in type 2 diabetes (T2DM) patients causes reactive oxygen species (ROS) accumulation, which causes the destruction of beta cells of the pancreas and contributes to T2DM. This study aimed to analyze the relationship between vitamin D deficiency (which is reciprocally related to Serum Uric Acid (SUA) levels), hyperuricemia, and levels of ROS scavengers in T2DM patients, and to investigate the effect of vitamin D supplementation on...

Background: Poor glycemic control in patients with type two diabetes mellitus (T2DM) is a strong risk risk factor for the development of complications and is associated with increased mortality. A growing body of evidence has demonstrated a role of the epidermal growth factor (EGF) in glucose homeostasis. The EGF contributes to the function, survival and proliferation of the β cells of the pancreas. The EGF also influences the action of insulin via the modulation of insul...

Purpose: Type two diabetes mellitus (T2DM) is a chronic disease of debilitating complications. Good glycemic control could delay disease progression and microvascular complications. Nonetheless, some patients cannot maintain glycemic control.Patients and Methods: We recruited 340 T2DM patients on metformin therapy and categorized them according to their HbA1c levels into patients with good vs poor glycemic control. The levels of serum leptin were measure...